Fig. 1: Trial profile.

aOf the six patients who did not complete neoadjuvant treatment, three withdrew consent, one discontinued due to physical condition, one due to medication unavailability, and one due to financial reasons. bOf the 10 patients who did not complete neoadjuvant treatment, nine discontinued due to adverse events, and one due to medication unavailability. ICT neoadjuvant immunochemotherapy, CRT neoadjuvant chemoradiotherapy.