Fig. 5: Sexually transmitted infections (STIs) and vaginal microbiome associated with ThinPrep Cytology Test (TCT) progress in longitudinal analysis. | Nature Communications

Fig. 5: Sexually transmitted infections (STIs) and vaginal microbiome associated with ThinPrep Cytology Test (TCT) progress in longitudinal analysis.

From: Vaginal microbiome and sexually-transmitted pathogens in Chinese reproductive-age women: a multicentre cross-sectional and longitudinal cohort study

Fig. 5: Sexually transmitted infections (STIs) and vaginal microbiome associated with ThinPrep Cytology Test (TCT) progress in longitudinal analysis.The alternative text for this image may have been generated using AI.

A Definition of outcomes in the longitudinal analysis, persistent negative vs new-onset is marked as (N) and transient vs persistent positive in marked as (P) in lower panels. B Baseline Shannon diversity and the progress of STIs (MH and HPV). C Baseline STI/ Shannon diversity and the progress of TCT. The analysis was performed in all samples (upper), HPV-negative samples (middle) and HPV-positive samples (bottom). The HR with 95% CI and p value are plotted for each association by cox-regression model. Results with p < 0.05 are highlighted. Full summary statistics can be found in Supplementary Data 23. Error bars represent the 95% CI. HR hazard ratio, CI confidence interval, MH Mycoplasma hominis, HPV Human papillomavirus, P persistent infection, N new-onset, TCT ThinPrep Cytology Test.

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