Fig. 6: Superior generalization of ERNIE-RNA on structurally dissimilar RNA datasets. | Nature Communications

Fig. 6: Superior generalization of ERNIE-RNA on structurally dissimilar RNA datasets.

From: ERNIE-RNA: an RNA language model with structure-enhanced representations

Fig. 6

a Scatter plot comparing per-sample binary F1-scores between fine-tuned ERNIE-RNA and fine-tuned RiNALMo on the bpRNA-new testset. Each point represents an individual RNA sequence, with ERNIE-RNA F1-scores on the x axis and RiNALMo F1-scores on the y axis. b A similar comparison on the RNA3DB-2D testset. c Visualization of RNA secondary structure predictions for two representative Rfam sequences: a pemK RNA (RF02913, top) from bpRNA-new dataset and a c-di-GMP-I riboswitch aptamer (RF01051, PDB 4YB1_R, bottom) from RNA3DB-2D testset. Ground truth structures (leftmost) are compared with predictions from ERNIE-RNA attn-map, ERNIE-RNA attn-map frozen, mxfold2, RNAfold, RNA-FM and RiNALMo. Binary F1-scores below each structure quantify prediction accuracy.

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