Fig. 7: The schematic diagram of nsp6-mediated coronaviral DMV growth.

nsp6 hijacks the ERAD machinery to stimulate lipolysis, thereby supplying both fatty acids and EDEM1-containing vesicles derived for the expansion of double-membrane vesicles (DMVs). The schematic diagram was created in BioRender. Liu, S. (2025) https://BioRender.com/acvqbf7.