Table 2 Treatment emergent adverse events (TEAE) occurring in >10% of patients receiving P-BCMA-ALLO1

From: TSCM-predominant allogeneic anti-BCMA CAR-T therapy for relapsed/refractory multiple myeloma: preclinical characterization and interim results from a phase 1 trial

TEAE, n (%) (N = 34)

All Grades

Grade ≥ 3

Treatment-related Grade ≥ 3

Anemia

12 (35.3)

9 (26.5)

7 (20.6)

Neutropenia

11 (32.4)

11 (32.4)

9 (26.5)

Leukopenia

10 (29.4)

10 (29.4)

8 (23.5)

Arthralgia

8 (23.5)

0 ((0)

0 (0)

Constipation

8 (23.5)

0 (0)

0 (0)

Diarrhea

8 (23.5)

0 (0)

0 (0)

Fatigue

8 (23.5)

0 (0)

0 (0)

Thrombocytopenia

8 (23.5)

4 (11.8)

1 (2.9)

Cytokine release syndrome (CRS)

7 (20.6)

0 (0)

0 (0)

Headache

7 (20.6)

0 (0)

0 (0)

Hypokalemia

7 (20.6)

0 (0)

0 (0)

Febrile neutropenia

5 (14.7)

5 (14.7)

3 (8.8)

Insomnia

5 (14.7)

0 (0)

0 (0)

Nausea

5 (14.7)

0 (0)

0 (0)

Peripheral edema

5 (14.7)

0 (0)

0 (0)

Chills

4 (11.8)

1 (2.9)

0 (0)

Dizziness

4 (11.8)

0 (0)

0 (0)

Pyrexia

4 (11.8)

0 (0)

0 (0)

Hypertension

4 (11.8)

1 (2.9)

0 (0)

Hypophosphatemia

4 (11.8)

0 (0)

0 (0)