Fig. 1: Whole genome sequencing (WGS) revealed unique gene alterations in rare subtypes. | Nature Communications

Fig. 1: Whole genome sequencing (WGS) revealed unique gene alterations in rare subtypes.

From: Comparative transcriptome atlas as an assistive modality for complex classification of rare kidney cancers

Fig. 1

a Images show representative H&E staining of histologically rare RCC and unclassified RCC analyzed in this study. Scale bars represent 100 μm. In each subtype, multiple cases exhibited similar histomorphology, and representative images are shown for each subtype. The number of cases in each subtype is displayed in Table 1. b Gene mutation matrix of WGS data is shown. Variants in kidney cancer-associated genes, chromatin remodeling genes, DNA repair-associated genes, p53 pathway-associated genes, SMAD pathway-associated genes, and Hippo-Yap pathway-associated genes are displayed. c Copy number alterations (CNA) of WGS data are shown. Amp amplification, LOH loss of heterozygosity, Rel. Loss relative loss, Abs. Loss absolute loss. Source data are provided in the Source data file.

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