Table 1 Scoring of seizure responses and division into mild, moderate, and severe seizures

From: Antecedent enhancer activity predicts future susceptibility to seizures in mice

Category

Score

Behavior

Mild seizure

0

Normal

1

Immobility

2

Twitching or trembling

3

Tail extension

4

Forelimb clonus

Moderate seizure

5

Generalized clonic activity

Severe seizure

6

Jumping and running

7

Full tonic extension

8

Death

  1. Using a modified Racine scale, responses to PTZ are scored from 0 to 8, spanning “normal” behavior to “generalized clonic activity” to “death”.
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