Table 2 Endometrial assessment of nine independent patients utilising the ERS2

From: Microengineered patient-derived endometrium-on-a-chip for the evaluation of endometrial receptivity and personalised translational medicine

ERS2

Patients

Normal

RIF and/or RPL

Main-Criteria

Sub-Criteria

Full Points

#1

#2

#3

#4

#5

#6

#A

#B

#C

#D

#E

#F

Endometrial Receptivity

Intensity of Integrin αvβ3

5

4

3

3

3

4

3

3

2

2

3

2

3

Intensity of Osteopontin

5

4

3

3

4

4

4

1

3

1

2

3

3

Blood vessel formation

Area of angiogenic sprout

5

3

3

4

4

4

3

1

3

1

1

1

1

Area of blood vessel

5

4

4

4

4

3

4

1

4

1

3

2

1

Total

20

15

13

14

15

15

14

6

12

5

9

8

8

ERS2

 

Receptive

Receptive

Receptive

Receptive

Receptive

Receptive

Non-Receptive

Receptive

Non-Receptive

Non-Receptive

Non-Receptive

Non-Receptive

ERS2: IVF-ET outcome prediction

 

Success

Success

Success

Success

Success

Success

Fail

Success

Fail

Fail

Fail

Fail

Clinical pregnancy outcome

 

Success

Success

Success

Success

N/A

N/A

Fail

Success

Fail

Fail

Fail

N/A