Table 4 Evaluation of clinically treated PRP efficacy using the EoC-ERS2

From: Microengineered patient-derived endometrium-on-a-chip for the evaluation of endometrial receptivity and personalised translational medicine

ERS2

Patient: RIF/RPL

Main-Criteria

Sub-Criteria

Full Points

NT-EoC

PRP treatment

T1-EoC

T2-EoC

T3-EoC

Endometrial Receptivity

Intensity of Integrin αvβ3

5

0

2

4

4

Intensity of Osteopontin

5

2

2

2

4

Blood vessel formation

Area of angiogenic sprout

5

2

3

3

4

Area of blood vessel

5

2

2

4

4

Total

20

6

9

13

16

ERS2

 

Non-Receptive

Non-Receptive

Receptive

Receptive

IVF-ET outcome prediction

 

Fail

Fail

Success

Success

Clinical pregnancy outcome

 

Fail

N/A

N/A

N/A (On-hold with issues of collecting good embryos)