Fig. 5: Network analysis of virus-symbiont interaction.
From: Biogeography and host interactions of CPR and DPANN viruses in acid mine drainage sediments
a SH-virus association network based on partial correlation analysis. Node shapes distinguish SHs (circles) from viruses (triangles). Edge width represents the absolute value of partial correlation coefficients, and edge color indicates positive (red) or negative (blue) associations. Only SHs identified by horizontal gene transfer (HGT) events are labeled. Bar chart shows the distribution of positive and negative associations in the network. Boxplot displays the distribution of absolute partial correlation coefficients for all significant associations, providing insight into the strength of host-virus relationships. Boxplot show the median (center line), 25th-75th percentiles (box limits), and 1.5×IQR whiskers. All individual data points are overlaid. b Linkages of YP2.bin58 (one populations from DPANN) and the infecting phage. The phage is linked by CRISPR-Cas system. Functional modules of I-G CRISPR-Cas system are masked by different colors. c Scatter plot of abundance correlation between the SHs of YP2.bin58 and YP4_provirus51. The linear correlations are determined using two-tailed Pearson tests. Pearson correlation coefficients and significance levels are displayed in each panel. Gray points: viral abundance outliers (1.5×IQR, n = 5). Purple line: significant Pearson correlation after outlier exclusion; gray line: overall trend. d Scatter plot of YP4_provirus51 abundance versus SHs-YP2.bin58 abundance ratio (log10 scale). Pearson correlation coefficients and significance levels are displayed in each panel.
