Fig. 1: Stability of folded proteins.

Analysis of backbone RMSD for Ubiquitin and Villin headpiece (HP35) simulated with the Amber ff03ws (A, B) and ff99SBws (C, D) across four independent simulations. The red dashed line indicates an RMSD of 0.2 nm, serving as the upper reference limit for conformational stability. Source data are provided as a Source data file.