Table 1 Optimization of the reaction conditions^a

^aEntries 1–7: Reaction was conducted using 1a (0.10 mmol) and 2a (0.12 mmol) under indicated conditions. Entries 8–10: Reaction was conducted using 1a (0.20 mmol) and 2a (0.10 mmol) under indicated conditions. Entries 12–17: Reaction was conducted using 1a (0.20 mmol) and 2a (0.10 mmol) under indicated conditions.
^b1a (0.25 mmol) and 2a (0.10 mmol), [Co-2] (6.0 mol%), TBPB (3.0 equiv), Mn(OAc)₂•4H₂O (0.6 equiv) were used.
^cIsolated yield.
^d1a (0.15 mmol) and 2a (0.10 mmol) were used.
^eA: Methyl 2,2-difluoro-2-(fluorosulfonyl)acetate.
^fB: Trimethylsilyl 2-(fluorosulfonyl)difluoroacetate.
^gC: 2-(Fluorosulfonyl)difluoroacetic acid.

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