Fig. 3: Translation dynamics during elongation.
From: Visualizing the translation landscape in human cells at high resolution
a 14 classes of human 80S ribosome in the translation elongation cycle, clipped to show tRNAs and factors bound. Solid arrows indicate pathways that have previously been reported. Dashed arrows are proposed pathways. The percentages indicate the proportion of particles in each class. The 60S and 40S subunits are shown in light and dark gray, respectively. The tRNAs are colored by position. b Comparison of the positions of tRNAs and translation elongation factors in each class, colored as in 2a. c 9 classes of hibernating states, with the E-tRNA bound rotated hibernating states (7a-11a) grouped together. d Translation state-dependent conformations of 28S rRNA G3922 (sticks). e Relative occupancy of the two conformations in different states.
