Fig. 4: Ribosome binding factors in cells.
From: Visualizing the translation landscape in human cells at high resolution
a Ribosome binding factors EDF1 (endothelial differentiation-related factor 1), EBP1 (ErbB3-binding protein 1), and NACβ (nascent polypeptide-associated complex β) were identified on ribosomes inside the cell. Representative cryo-EM maps (surface) and structural models (cartoon and sticks) are shown. Two patches of unknown density with fitted molecular model are shown in cyan (bottom). b eIF6 (eukaryotic initiation factor 6) (pink) and EBP1 densities in free 60S particles in the untreated cells. c Conformations of h16 of 18S rRNA and EDF1 observed in situ and in vitro.
