Fig. 5: Detailed interaction interface of di-ribosomes.
From: Visualizing the translation landscape in human cells at high resolution
a Structures of two types of di-ribosomes. i indicates the leading ribosome, i + 1 indicates the trailing ribosome. Class1 is a top-back (t-b) interaction and Class2 is a top-top (t-t) interaction. b Interaction interfaces of the two types of di-ribosomes. The t-b class has mainly inter-ribosomal 60S-40S subunit interactions, whereas the t-t class has mainly 40S-40S subunit interactions. c Comparison of the two classes of di-ribosomes. d Helical Class1 ribosome density appears when data processing was done with a large box. e The t-t interaction is incompatible with the helical structure shown in d, whereas the t-b interaction can form this high-order helical ribosome structure.
