Fig. 7: The structures of TkoTpt1 in complex with nucleotides containing 2’,3’,5’-PO4. | Nature Communications

Fig. 7: The structures of TkoTpt1 in complex with nucleotides containing 2’,3’,5’-PO4.

From: Crystal structures and snapshots along Tpt1-catalyzed phosphate transfer from nucleic acid to NAD+

Fig. 7: The structures of TkoTpt1 in complex with nucleotides containing 2’,3’,5’-PO4.The alternative text for this image may have been generated using AI.

a Detailed interactions between TkoTpt1 and 2’,3’,5’-p-A in the TkoTpt1/2’,3’,5’-p-A complex. b Detailed interactions between TkoTpt1 and 2’,3’,5’-p-U in the TkoTpt1/2’,3’,5’-p-U complex. c Detailed interactions between TkoTpt1 K63A mutant and 2’,3’,5’-p-A and ADPR in the K63A/2’,3’,5’-p-A/ADPR complex. d Detailed interactions between TkoTpt1 K63A mutant and the 2’-p-ADPR-RNA intermediate in the K63A/2’-p-ADPR-RNA complex.

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