Fig. 8: The mechanism for TkoTpt1-catalyzed nucleic acid 5’-PO42- transfer.
From: Crystal structures and snapshots along Tpt1-catalyzed phosphate transfer from nucleic acid to NAD+
a Superposition of the K63A/5’-p-ADPR-DNA complex and the K63A/2’-p-ADPR-RNA complex. b Conformational comparison of the two intermediates and their interacting residues. c Proposed mechanisms for TkoTpt1-catalyzed nucleic acid 5’-PO42- transfer.
