Fig. 3: Insulin resistance measures at baseline and after 26 weeks by treatment group. | Nature Communications

Fig. 3: Insulin resistance measures at baseline and after 26 weeks by treatment group.

From: Effect of metformin on insulin resistance in adults with type 1 diabetes: a 26-week randomized double-blind clinical trial

Fig. 3

The graphs show the pre- and post-treatment endogenous glucose production (Panel A), glucose infusion rate (Panel B) and non-esterified fatty acids (Panel C) in the participants with type 1 diabetes treated with metformin or placebo (Panel D, E and F). Metformin had no significant effect on measures of liver, muscle or adipose insulin resistance. Analyses are two-sided using generalized linear mixed modelling without adjustment for multiple testing. Data are presented as means and 95% confidence intervals.

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