Fig. 1: Periodic asymmetric fields enhance nanoscale electrofusion of lipid nanoparticle systems.
From: Periodic asymmetric field enhances electrofusion of nanoscale lipid systems
a Schematic of a nanoscale lipid system and electrofusion process in the periodic asymmetric fields consisting of a microfluidic flow field and a periodic electric field. b Schematic diagram of a multi-physics simulation model based on computational fluid dynamics. c Schematic of a periodic asymmetric fields inspired microfluidic electrofusion device (PAF-MED). The schematic in (a and c was created by the authors using Adobe Illustrator software (version 2023). d Representative cryo-TEM image of cell membrane hybrid lipid nanoparticles (cLNPs) synthesized with PAF-MED (scale bar, 100 nm). Representative data of three independent experiments are shown.
