Fig. 4: Manhattan plot for migraine GWAS with highlighted SNPs predicted by InsightGWAS.
From: Transformer-based deep learning enhances discovery in migraine GWAS
a Manhattan plot for the migraine GWAS from Hautakangas et al. (excluding 23andMe data), highlighting variants predicted by InsightGWAS in orange. b Manhattan plot for independent signals (clumped SNPs) predicted by InsightGWAS, with key loci highlighted in orange. Genes associated with these key loci are functionally annotated and categorized into Neurotransmitter Signaling and Synaptic Regulation (green), Neurodevelopment and Synaptic Connectivity (purple), and Ion Transport and Cellular Signaling (blue). Note: The association p-values displayed are from the original GWAS; no new statistical tests were applied for this visualization.
