Fig. 2: Differential metabolites and key metabolic pathways of second-trimester multivariate samples in GDM. | Nature Communications

Fig. 2: Differential metabolites and key metabolic pathways of second-trimester multivariate samples in GDM.

From: Metabolomics of saliva, serum, and urine for pathogenesis, diagnosis, and prognosis in gestational diabetes mellitus

Fig. 2: Differential metabolites and key metabolic pathways of second-trimester multivariate samples in GDM.The alternative text for this image may have been generated using AI.

a Venn diagram showed that seven saliva metabolites, 40 serum metabolites, and seven urine metabolites were significantly altered in both the cohort 1 and cohort 2, which were considered differential metabolites. b Diagram of metabolic pathway disorder mechanism. Arrows indicated the flow of differential metabolites. Blue nodes represented metabolites with significant changes in saliva, red nodes represented metabolites that have significantly changed in serum, and yellow nodes represented metabolites with significant changes in urine. The arrows next to metabolite names indicate their trend of change in GDM. The dark blue nodes represented key metabolites of metabolic pathways that can act as mediators linking differential metabolites. Source data were provided as a Source Data file.

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