Fig. 7: The heading direction network in the aHB functions in the absence of habenular input. | Nature Communications

Fig. 7: The heading direction network in the aHB functions in the absence of habenular input.

From: Visual motion and landmark position align with heading direction in the zebrafish interpeduncular nucleus

Fig. 7: The heading direction network in the aHB functions in the absence of habenular input.

a Left, z projection of the brain of a Tg(gad1b:Gal4; 16715:Gal4; UAS:GCaMP6s) fish expressing GCaMP6s both in habenular neurons and GABAergic neurons before two-photon ablation. Right, z projection of the brain of a different fish following a two-photon ablation of the FR. Red arrows indicate the two sites of laser ablation. Note habenular axons are gone from the IPN. b aHB anatomy overlaid with HDNs colored according to their phase. c Neural dynamics following two-photon ablation of habenular input in three fish. For each fish: top, tail trace showing the motor activity of the fish during the experiment. Bottom, traces of heading direction neurons sorted according to their phase showing the activity bump changing as the fish turns. Black scale bar for each fish indicated 100 seconds of recording.

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