Fig. 3: Association between cg25114611/cg25563198, FKBP5 gene expression and disease risk.
From: DNA methylation predicts adverse outcomes of coronary artery disease
a The correlation between DNA methylation level of cg25114611 and FKBP5 gene expression in whole blood (n = 391). Light green shading represents the 95% confidence intervals. b The correlation between DNA methylation level of cg25563198 and FKBP5 gene expression in whole blood (n = 391). Light green shading represents the 95% confidence intervals. a, b P-values were calculated using a two-sided Pearson’s correlation coefficient assays. c Differential expression analysis of FKBP5 gene between normal and myocardial infarction participants in peripheral blood (ncontrol = 10, nMI = 7). In the boxplot of panels, hinges indicate the 25th, 50th, and 75th percentiles, whiskers indicate 1.5× interquartile ranges. d Differential expression analysis of FKBP5 gene between control and ischemic stroke participants in peripheral blood (ncontrol = 24, nStroke = 39). In the boxplot of panels, hinges indicate the 25th, 50th, and 75th percentiles, whiskers indicate 1.5× interquartile ranges. c, d P-values were calculated using a two-sided Wilcoxon test. e Gene expression of FKBP5 in various cell types as the disease progression of myocardial infarction in heart tissue. MI myocardial infarction. Source data were provided as a Source Data file.
