Table 3 Performance of the prognostic model for death
From: DNA methylation predicts adverse outcomes of coronary artery disease
CG + Sex + Age model: | |||||||
|---|---|---|---|---|---|---|---|
Reference | Discovery set | Validation set | |||||
Predictive | Survival | Death | Total | Survival | Death | Total | |
Survival | 151 | 58 | 209 | 342 | 9 | 351 | |
Death | 37 | 159 | 196 | 161 | 16 | 177 | |
Totals | 188 | 217 | 405 | 503 | 25 | 528 | |
Sensitivity | 73.27% | 64% | |||||
Specificity | 80.32% | 67.99% | |||||
Cutoff value | 1.267 | ||||||
Ensemble model: | |||||||
|---|---|---|---|---|---|---|---|
Reference | Discovery cohort | Validation cohort | |||||
Predictive | Survival | Death | Total | Survival | Death | Total | |
Survival | 132 | 49 | 181 | 174 | 4 | 178 | |
Death | 23 | 137 | 160 | 57 | 9 | 66 | |
Totals | 155 | 186 | 341 | 231 | 13 | 244 | |
Sensitivity | 73.66% | 69.23% | |||||
Specificity | 85.16% | 75.32% | |||||
Cutoff value | 1.10 | ||||||
