Fig. 2: Heatmap visualization of gene correlation pairs for each drug, with correlation values indicated by color coding. | Nature Communications

Fig. 2: Heatmap visualization of gene correlation pairs for each drug, with correlation values indicated by color coding.

From: Biologically-informed integration of drug representations for breast cancer treatment using deep learning

Fig. 2: Heatmap visualization of gene correlation pairs for each drug, with correlation values indicated by color coding.The alternative text for this image may have been generated using AI.

Rows and columns are clustered using consensus clustering, drugs are annotated by type, the numbers of gene correlation pairs are annotated by color and shown in the bracket after drug name. Source data are provided as a Source Data file. PDCD1 represents anti-PD-1/PD-L1 therapy (pembrolizumab and durvalumab). ANG represents an ANG peptide inhibitor (AMG-386). VEGFA represents an anti-VEGFA antibody (bevacizumab). IGF1R represents anti-IGF1R antibody (ganitumab). Capecitabine is represented by 5-fluorouracil. Ganetespib is represented by luminespib. Ixabepilone is represented by epothilone B.

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