Fig. 2: Self-assembly of TPA-S-DCR. | Nature Communications

Fig. 2: Self-assembly of TPA-S-DCR.

From: A hindrance-plane-hindrance molecular engineering strategy towards self-assembled nanorods for enhanced photodynamic therapy

Fig. 2: Self-assembly of TPA-S-DCR.

a Optimized chemical structure of TPA-S-DCR. b TEM images showing the spherical to rod-shaped morphology transition with the increase of sonication time at TPA-S-DCR concentration of 1.0 mg/mL) (Scale bar: 250 nm). c TEM images showing the self-assemble behaviors of TPA-S-DCR at different molecular concentration (under 2 min sonication) (Scale bar: 250 nm). d TEM images showing the self-assemble behaviors of TPA-S-DCR (1.0 mg/mL) under 0 °C and 80 °C (Scale bar: 250 nm). e TEM imaging showing the morphology evolution of TPA-S-DCR self-assemblies with the evaporation of THF (Scale bar: 250 nm). f Molecular dynamic simulation (GROMACS) of TPA-D-DCR self-assembly with the increased molecule number increase within simulation box. g Schematic of influence factors towards TPA-S-DCR self-assembly. For TEM imaging, n = 3 independent experiments. Created in BioRender. Mou, X. (2025) https://BioRender.com/tf1dnvd.

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