Fig. 6: Tumor enrichment and penetration of TSD-Rod and TSD-Sphere. | Nature Communications

Fig. 6: Tumor enrichment and penetration of TSD-Rod and TSD-Sphere.

From: A hindrance-plane-hindrance molecular engineering strategy towards self-assembled nanorods for enhanced photodynamic therapy

Fig. 6: Tumor enrichment and penetration of TSD-Rod and TSD-Sphere.

a In vivo near infrared images of tumor enrichment of TSD-Rod/TSD-Sphere. b Tumor enrichment profiles of TSD-Rod/TSD-Sphere. Data are presented as mean ± SD (n  =  3 mice). The intensity of TSD-Sphere was normalized with TSD-Rod to eliminate their fluorescence difference. c Ex vivo fluorescence images of organs and tumors at 12 h post injection. d Histograms of TSD-Rod/TSD-Sphere distribution in (c). The intensity of TSD-Sphere was normalized with TSD-Rod to eliminate their fluorescence difference. Data are presented as mean ± SD (n  =  3 mice). a.u. refers to arbitrary unit. Two-tailed Student’s t test was performed for comparisons between two groups. A significance level of p  <  0.05 was utilized for determining statistical significance. e CLSM images of tumor slices at different depths (Scale bar: 2 mm for overview, 100 μm for enlarged region) (n = 3 independent experiments). Created in BioRender. Mou, X. (2025) https://BioRender.com/tf1dnvd. Source data are provided in Source Data file.

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