Fig. 4: GSEA of single nuclei RNA & ATAC sequencing. | Nature Communications

Fig. 4: GSEA of single nuclei RNA & ATAC sequencing.

From: Palbociclib and endocrine therapy diminish adaptive anti-tumor immunity in early breast cancer: The NeoRHEA phase 2 study

Fig. 4

a Gene Set Enrichment analysis, GSEA (hallmark gene sets) based on differential gene expression between baseline and surgery samples using single-nuclei RNA-seq (only data on E2F targets and G2M checkpoint gene sets are presented). b GSEA (hallmark gene sets) based on genes identified in differentially accessible peaks between baseline and surgery samples using single-nuclei ATAC-seq (only data on E2F targets and G2M checkpoint gene sets are presented). Color denotes the significance level (Q value). The X-axis denotes the normalized enrichment score (NES) of each of the gene sets shown on the Y-axis. Source data are provided as supplementary Table 8, 11.

Back to article page