Table 5 Sensitivity analysis on difference-in-difference estimates of intervention effects on treatment outcomes over time

From: Impact of a community-based antiretroviral therapy delivery model for people living with HIV in Cambodia

 

Scenario 1a

Scenario 2b

Scenario 3c

 

DiD estimate (%) [95% CI]

DiD estimate (%) [95% CI]

DiD estimate (%) [95% CI]

ART adherence

   

Self-reported ART adherence

6.6 [5.2, 7.8]

6.4 [5.0, 7.8]

8.1 [6.7, 9.6]

HIV-related stigma (people living with HIV Stigma Index)

Non-stigma experienced

4.9 [3.3, 6.6]

4.6 [2.9, 6.1]

6.3 [4.5, 8.1]

Low internal stigma

−0.8 [−2.2, 0.4]

−0.9 [−2.4, 0.3]

1.1 [−0.3, 2.3]

Not fear of stigma

−0.8 [−2.0, 0.5]

−1.4 [−2.6, −0.0]

0.6 [−0.7, 1.8]

Mental health status (CES-D)

No depression symptoms

6.9 [5.5, 8.5]

6.7 [5.2, 8.3]

8.3 [6.9, 10.0]

Quality of life (SF-12)

Good mental health

3.5 [2.2, 4.9]

3.9 [2.5, 5.2]

3.5 [2.1, 4.8]

Good physical health

11.9 [10.6, 13.3]

11.6 [10.1, 13.1]

11.9 [10.5, 13.3]

  1. AOR adjusted odds ratio, ART antiretroviral therapy, BIC Bayesian information criterion, CAD community-based ART delivery, CES-D Center for Epidemiologic Study Depression Scale, CI confidence interval, MMD multi-month dispensing, OR odds ratio, SF-12 12-item Short Form survey.
  2. aAssumptions: (i) Missing at random. (ii) Baseline characteristics remained unchanged at endline.
  3. bAssumptions: (i) Missing at random. (ii) Some baseline characteristics changed at endline for 50% of participants with incomplete endline surveys.
  4. cAssumptions: (i) Missing not at random, where participants with incomplete endline surveys had worse outcomes (e.g. 5% lower probability of adherence) than observed data at endline. (ii) Baseline characteristics remained unchanged at endline.
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