Fig. 4: Alteration in H3K27me3, H2A.Z, or H2Aub levels do not affect H3K4me2.

a Scatter plots showing H3K27me3 and H3K4me2 levels comparing jmj30 jmj32 elf6 ref6 jmj13 quintuple mutants (jmj quintuple) and WT. Each dot represents a protein-coding gene. Red dots indicate JMJ-target genes (n = 3048, as shown in Supplementary Fig. 4a). b Metaplots showing the averaged distribution of H3K27me3 and H3K4me2 in JMJ-target genes (n = 3048) in WT and jmj quintuple. c Scatter plots showing H3K27me3 and H3K4me2 levels comparing clf and WT. Each dot represents a protein-coding gene. Blue dots indicate CLF-target genes (n = 2160, as shown in Supplementary Fig. 4b). d Metaplots showing the averaged distribution of H3K27me3 and H3K4me2 in CLF-target genes (n = 2160) in WT and clf. e Scatter plots showing H2A.Z and H3K4me2 levels comparing pie1 and WT. Each dot represents a protein-coding gene. Blue dots indicate SWR1-C-target genes (n = 6096, as shown in Supplementary Fig. 5c). The regions from TSS to TSS + 500 bp were analyzed. f Metaplots showing the averaged distribution of H2A.Z and H3K4me2 in SWR1-C-target genes (n = 6096) in WT, arp6, and pie1. g Scatter plots showing H2Aub and H3K4me2 levels comparing WT and atbmi1a/b/c. Each dot represents a protein-coding gene. Blue dots indicate AtBMI1-target genes (n = 4982, as shown in Supplementary Fig. 6a). h Metaplots showing the averaged distribution of H2Aub and H3K4me2 in AtBMI1-target genes (n = 4982) in WT and atbmi1a/b/c. The values of scatter plots and metaplots represent RPKM.