Table 2 Pathologic response at surgery

From: Efficacy, safety, and predictive biomarkers of neoadjuvant nab-paclitaxel and pembrolizumab in hormone receptor-positive breast cancer: A randomized pilot trial

RCB class

All patients (n = 29)

No. of patients (%)

Arm A (chemotherapy first) (n = 15)

No. of patients (%)

Arm B (immunotherapy first) (n = 14)

No of patients (%)

 

Received neoadj AC (n = 15)

No neoadj AC (n = 14)

Received neoadj AC (n = 9)

No neoadj AC (n = 6)

Received neoadj AC (n = 6)

No neoadj AC (n = 8)

0 (aka pCR)

2 (13.3%)

3 (21.4%)

0 (0.0%)

2 (33.3%)

2 (33.3%)

1 (12.5%)

1

1 (6.7%)

2 (14.3%)

1 (11.1%)

1 (16.7%)

0 (0.0%)

1 (12.5%)

2

6 (40.0%)

4 (28.6%)

5 (55.6%)

1 (16.7%)

1 (16.7%)

3 (37.5%)

3

5 (33.3%)

5 (35.7%)

2 (22.2%)

2 (33.3%)

3 (50.0%)

3 (37.5%)

Not evaluable*

1 (6.7%)

0 (0.0%)

1 (11.1%)

0 (0.0%)

0 (0.0%)

0 (0.0%)

  1. *One patient was found to have metastatic disease prior to surgery, thus did not undergo surgery and is not evaluable for RCB status.
  2. RCB residual cancer burden, AC doxorubicin + cyclophosphamide, neoadj neoadjuvant, pCR pathologic complete response.