Fig. 1: Proteins associated with mortality in CRIC. | Nature Communications

Fig. 1: Proteins associated with mortality in CRIC.

From: Risk factors for mortality in patients with kidney failure on hemodialysis identified by proteomic analysis of CRIC and PACE studies

Fig. 1: Proteins associated with mortality in CRIC.The alternative text for this image may have been generated using AI.

Volcano plot illustrates proteins associated with mortality in 436 CRIC participants with kidney failure on hemodialysis ≥1 year, using 14-year follow-up, log2 normalization, no adjustment for covariates. There are 27 proteins significant at p < 7 × 10-6 and 184 at FDR < 0.05. GDF growth differentiation factor, SVEP1:Sushi von Willebrand factor type A EGF and pentraxin domain-containing protein 1, IGFALS insulin-like growth factor-binding protein complex acid labile subunit, C7 complement component C7, TGFB1 transforming growth factor-β1. Associations tested with Cox HR and two-sided p-values.

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