Fig. 4: Sex-biased gene expression in sex-converted GSS pseudomales. | Nature Communications

Fig. 4: Sex-biased gene expression in sex-converted GSS pseudomales.

From: Mosquito sex separation using complementation of selectable traits and engineered neo-sex chromosomes

Fig. 4

A Spearman correlation matrix of genome-wide expression in sequenced samples. Higher correlation values indicate greater similarity in transcriptomic profiles. B RNA-seq coverage plot for sex-linked markers (myo-fem, myo-sex, yellow) and key sex-determination genes (nix, doublesex, fruitless). Exons are indicated in gray, except for female-specific exons that are indicated in pink. Introns not to scale. Coverage for male samples is shown on the positive Y-axis, while female coverage is reflected on the negative Y-axis for clarity. C Differential expression analysis comparing wild-type (WT) females versus WT males (top) or genetic sexing strain (GSS) pseudomales (bottom), indicating changes or retention of sex-biased direction between analyses. Source data are provided as a Source Data file.

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