Fig. 2: Genome mining of bacterial P450sccs.
From: Unveiling cytochrome P450 enzymes that catalyze steroid side-chain cleavage in bacteria

a A strategy for mining P450s for steroid functionalization from steroid-degrading bacterial genomes. (b) The structures of the steroid substrates used in this study. c Phylogenetic tree of potential bacteria-derived P450scc proteins. The phylogenetic tree was built from the protein sequences of P450-A8 (CYP204A2, accession number: CCA90294.1, blue) and its homologs with amino acid sequence identity greater than 40%, using the Maximum Likelihood Method. The CYP204A2 homologous proteins chosen for this analysis are colored red.