Table 2 NAM binding constants (Ki) from [3H]-AP competition binding assays for binding site mutants

From: Visualizing insecticide control of insect TRP channel function and assembly

 

Affinity with 95% confidence intervals

 

Ki NAM (mM)

Lower CI

Upper CI

WT

0.11

0.05

0.23

NanY172A

8.74

4.98

15.56

NanY172F

0.88

0.52

1.49

NanY177A

>10

ND

ND

NanY177F

1.12

0.68

1.82

IavW323A

>10

ND

ND

IavY325A

>10

ND

ND

  1. Values correspond to plots in Fig. 2e and are derived from plots in Supplementary Fig. 11. Source data are provided as a Source data file.
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