Table 3 [3H]-AP binding (Kd) constants for binding site mutants

From: Visualizing insecticide control of insect TRP channel function and assembly

 

Affinity with 95% confidence intervals

 

Kd AP (nM)

Lower CI

Upper CI

WT

0.017

0.012

0.023

NanY172A

1.28

1.06

1.55

NanY172F

0.040

0.032

0.051

NanY177A

4.05

2.01

9.12

NanY177F

0.015

0.011

0.020

IavW323A

0.20

0.13

0.30

IavY325A

0.70

0.39

1.32

  1. Values correspond to plots in Fig. 3e and are derived from plots in Supplementary Fig. 11. Source data are provided as a Source data file.