Table 3 [3H]-AP binding (Kd) constants for binding site mutants
From: Visualizing insecticide control of insect TRP channel function and assembly
| Â | Affinity with 95% confidence intervals | ||
|---|---|---|---|
| Â | Kd AP (nM) | Lower CI | Upper CI |
WT | 0.017 | 0.012 | 0.023 |
NanY172A | 1.28 | 1.06 | 1.55 |
NanY172F | 0.040 | 0.032 | 0.051 |
NanY177A | 4.05 | 2.01 | 9.12 |
NanY177F | 0.015 | 0.011 | 0.020 |
IavW323A | 0.20 | 0.13 | 0.30 |
IavY325A | 0.70 | 0.39 | 1.32 |