Table 4 AP binding constants (Ki) from [3H]-AP competition binding assays for binding site mutants

From: Visualizing insecticide control of insect TRP channel function and assembly

 

Affinity with 95% confidence intervals

 

Kd AP (nM)

Lower CI

Upper CI

WT

0.010

0.0077

0.013

NanY172A

0.65

0.28

1.49

NanY172F

0.030

0.016

0.056

NanY177A

3.23

1.13

10.57

NanY177F

0.014

0.0097

0.020

IavW323A

0.19

0.12

0.31

IavY325A

1.92

0.97

3.81

  1. Values are derived from plots in Supplementary Fig. 11. Source data are provided as a Source data file.
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