Fig. 5: The Manhattan plot of phenome-wide association study and GeneMania gene network for candidate genes.
From: Genetic insights and mechanistic parallels in gestational diabetes mellitus and type 2 diabetes
A The Manhattan plot of phenome-wide association between COBLL1 and UKB binary traits. B The Manhattan plot of phenome-wide association between COBLL1 and UKB continuous traits. C The Manhattan plot of phenome-wide association between NRBP1 and UKB binary traits. D The Manhattan plot of phenome-wide association between NRBP1 and UKB continuous traits. E The Manhattan plot of phenome-wide association between IFT172 and UKB binary traits. F The Manhattan plot of phenome-wide association between IFT172 and UKB continuous traits. G The Manhattan plot of phenome-wide association between TRIM54 and UKB binary traits. H The Manhattan plot of phenome-wide association between TRIM54 and UKB continuous traits. Generalized linear model is used for phenome-wide association study. Each test is two-sided and the original P value is reported with no multiple comparisons. I GeneMania gene network of COBLL1 as the core. J GeneMania gene network of NRBP1 as the core. K GeneMania gene network of IFT172 as the core. L GeneMania gene network of TRIM54 as the core. UKB UK Biobank.
