Fig. 4: Cohabitation compresses population variance. | Nature Communications

Fig. 4: Cohabitation compresses population variance.

From: Accumbal calcium-permeable AMPA receptors orchestrate neuronal ensembles underlying social attachment

Fig. 4

A Number of PCs required to explain 95% of variance exhibited during social interaction, normalized by number of neurons. Mixed LM main effect time Day 2 β = –0.269, p = 1.17*10^–8. Main effect treatment β = 0.060, p = 0.149. B Variance during social interaction explained by first 3 PCs. Mixed LM main effect time Day 2 β = 0.125, p = 0.022. Main effect treatment β = 0.009, p = 0.840. Mixed LM, interaction between number of PCs and variance explained by first 3 PCs, β = –0.449, p = 0.0014. C Representative animal, partner and stranger representations in PC space. D Separability of partner and stranger centroids in first 3 PCs, represented by p-values derived from comparing the actual distance to a null distribution. Vehicle one-sample vs 0.5, t(7) = 1.076, p = 0.318, IEM-1460 t(6) = 1.679, p = 0.144. Dashed lines indicate 5th and 95th percentiles. p = 0.0149. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. Data are presented as mean values ± SEM.

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