Fig. 5: Mesothelial and mesenchymal progenitor cells orchestrate tissue homeostasis in the benign omentum via a repertoire of signaling pathways. | Nature Communications

Fig. 5: Mesothelial and mesenchymal progenitor cells orchestrate tissue homeostasis in the benign omentum via a repertoire of signaling pathways.

From: Ovarian cancer metastasis to the human omentum disrupts organ homeostasis and induces fundamental tissue reprogramming

Fig. 5: Mesothelial and mesenchymal progenitor cells orchestrate tissue homeostasis in the benign omentum via a repertoire of signaling pathways.The alternative text for this image may have been generated using AI.

Cell-cell-communication interactions between major cell types inferred by CellChat (‘non-metastasized omentum’ subcohort, n = 17). Aggregate communication networks of non-metastasized samples depicting the number (A) and the strength (B) of interactions between major cell types. A threshold of 0.5% cells per cell type out of the total was applied. Major outgoing (C) and incoming (D) patterns shared between cell types and their pathway contributions. Circos plots summarizing outgoing mesothelial cell (E) and MSPCs (F) communication pathways. See also Supplementary Fig. 9. Source data are provided as a Source Data file.

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