Fig. 3: GWAS results. | Nature Communications

Fig. 3: GWAS results.

From: Genetic Insights into Head-to-Body Ratios Via Deep Learning-Based Image Segmentation and Implications for Common Diseases

Fig. 3: GWAS results.The alternative text for this image may have been generated using AI.

a Combined Manhattan plot for all HBRs, where only the nearest coding genes to the most significant SNPs within 5 Mb are annotated. We randomly sampled 50,000 SNPs with −log10(p)≤5, and retained all SNPs with −log10(p)>5. GWAS p-values were calculated using BOLT-LMM. b The total number of genome-wide significant SNPs (Ngw, SNP) and loci (locus) for each HBR, along with the intercept calculated by LDSC. c Bar plot shows the SNP heritability of each HBR. The estimated heritability and its standard error (error bars) are derived from LDSC.

Back to article page