Table 2 Summary of response (n = 40)

From: Neoadjuvant immune checkpoint blockade before chemoradiation for cervical squamous carcinoma (GINECO window-of-opportunity COLIBRI study): a phase II trial

Response

No. (%) [95% CI]

 

Within 1 week before chemoradiation

4 weeks after chemoradiation

End of treatment

Global

 Complete response

0

26 (65) [48–79]

31 (78) [62–89]

  Stage I/II

0

10/14 (71) [42–92]

11/14 (79) [49–95]

  Stage III/IV

0

16/26 (62) [41–80]

20/26 (77) [56–91]

 Partial response

5 (13) [4–27]

13 (33) [19–49]

5 (13) [4–27]

  Stage I/II

1/14 (7) [0–34]

4/14 (29) [8–58]

3/14 (21) [5–51]

  Stage III/IV

4/26 (15) [4–35]

9/26 (35) [17–56]

2/26 (8) [1–25]

 Stable disease

33 (83) [67–93]

1 (3) [0–13]

0

  Stage I/II

11/14 (79) [49–95]

0

0

  Stage III/IV

22/26 (85) [65–96]

1/26 (4) [0–20]

0

 Disease progression

2 (5) [1–17]

0

4 (10) [3–24]

  Stage I/II

2/14 (14) [2–43]

0

0

  Stage III/IV

0

0

4/26 (15) [4–35]

Local

 Complete response

0

27 (68) [51–81]

34 (85) [70–94]

 Partial response

6 (15) [6–30]

12 (30) [17–47]

3 (8) [2–20]

 Stable disease

32 (80) [64–91]

1 (3) [0–13]

1 (2) [0–13]

 Disease progression

2 (5) [1–17]

0

2 (5) [1–17]