Fig. 4: Quantifying resistance in E. coli. | Nature Communications

Fig. 4: Quantifying resistance in E. coli.

From: Quantifying the bystander effect of antimicrobial use on the gut microbiome and resistome in Malawian adults

Fig. 4

A Comparing the diversity of the metagenome-assembled E. coli genomes to genomes from ESBL-selective culture using popPUNK; number of samples (y-axis) for a given popPUNK cluster (x-axis) show that the metagenome-assembled genomes are more diverse. B Prevalence of AMRFinder gene subclass in samples with a high-quality E. coli metagenome-assembled genome (n = 259) with exact binomial 95% confidence intervals. C Parameter values and 95% credible intervals from fitted models quantifying the effect of exposures (panels) on the presence of AMR gene subcategory in E. coli metagenome-assembled genomes. Coefficients are on the log scale and can be interpreted as exposure resulting in a log odds ratio for the presence of a given gene. A value of 0 (dotted line) is no change. The number of participants included in the analysis is given in Supplementary Table 3.

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