Fig. 4: Effect of the CD36 intron1-intron3 deletion on blood cell phenotypes in 6141 Qatari samples (a–h).
From: The biomedical landscape of genomic structural variation in the qatari population
a A 23-kb deletion (AF 0.01759) identified on chromosome 7 and located in region between intron 1 and intron 3 of the CD36 gene showed decreased expression in heterozygous and homozygous carriers in proteomics data. Based on reported phenotypes in OMIM, we performed a quantitative analysis of the effect of this deletion on blood cell-related phenotypes. a white blood cells (N = 5995); b red blood cells (N = 5995); c mean cell hemoglobin concentration (N = 5995); d mean cell hemoglobin (N = 5995); e platelet counts (N = 5923); f mean platelet volume (N = 5994); g hemoglobin (N = 5994); h hematocrit (N = 5995); and i neutrophil hematocrit (N = 5990). P-values were calculated using Kruskal–Wallis test. Boxplots show the different values between three genotypes. The center line in the box indicates the median, the lower and upper hinges indicate the first and third interquartile range (IQR).
