Fig. 1: Comprehensive neuronal transcriptomic atlas of mouse somatosensory cortex development. | Nature Communications

Fig. 1: Comprehensive neuronal transcriptomic atlas of mouse somatosensory cortex development.

From: Uncovering the molecular logic of cortical wiring between neuronal subtypes across development through ligand–receptor inference

Fig. 1

A Sankey diagram depicting the experimental paradigm for data collections and integration of published datasets. Yao*: Yao et al., 2021; J. Di Bella*: J. Di Bella et al., 2021, Telley*: Telley et al., 2019; R.Lee*: R.Lee et al., 2022; Bandler: Bandler et al., 2021; Mayer*: Mayer et al., 2018; Mi*: Mi et al., 2018; SSp primary somatosensory cortex, SSs supplemental somatosensory cortex, MGE medial ganglionic eminence, dMGE dorsal MGE, vMGE ventral MGE, CGE caudal ganglionic eminence, LGE lateral ganglionic eminence, 10X 10X Genomics, SSv4 Smart-seq version 4, SSv2 Smart-seq version 2, C1 Fluidigm C1. B UMAP visualization of post-mitotic neurons from the 17 time points after integration. Cells are colored by cell-type assignment. C UMAP visualization is colored by age, study, region, RNA-seq method, sequencing platform, and gene markers. D Left: Sankey plot representing the different hierarchical levels of cell type assignment; middle: heatmap representing the fraction of each cell type per age; right: heatmap representing some cell type-specific genes. “Normalized expression” represents the 25% trimmed mean log2(CPM + 1) expression normalized by row. See also Figs. S1–S4. Associated source data are provided.

Back to article page