Fig. 2: Scope of Ni/Co dual-electrocatalyzed dehydrogenative allylation.
From: Tunable enantioselective electrocatalytic functionalization of unactivated alkenes
Reactions were performed by using 1 (0.1 mmol), 2 (0.5 mmol), Ni(OAc)2·4H2O (10 mol%), L5 (11 mol%), A5 (20 mol%), morpholine (0.1 mmol), and nBu4NBF4 (0.1 M) in THF/TFE under constant-current conditions (1.5 mA) in an undivided cell, 4.5 F/mol. Isolated yields after chromatography are shown. a2 (1.2 mmol). b10 °C. cA2 (10 mol%), 2 (1.5 mmol) and without base. d-10 °C. eA4 (10 mol%), 2 (1.5 mmol), and 2,6-Lutidine (0.1 mmol) in MeOH/TFE. fA3 (20 mol%), L2 (11 mol%), and 2 (2 mmol), without base in DCE/TFE. gL3 (11 mol%), 2,6-Lutidine (0.1 mmol).
