Fig. 4: Co-occurrence patterns among defense systems in cold seep prokaryotes. | Nature Communications

Fig. 4: Co-occurrence patterns among defense systems in cold seep prokaryotes.

From: Co-occurrence of diverse defense systems shapes complex microbe-virus relationships in deep-sea cold seeps

Fig. 4: Co-occurrence patterns among defense systems in cold seep prokaryotes.

a Correlations among 34 defense systems in cold seep prokaryotes. The lower-left matrix (blue-red gradient) displays correlations among all defense systems across prokaryotic MAGs, while the upper-right matrix (green-pink gradient) shows correlations within defense islands. Pearson correlation coefficients were calculated based on system abundance using two-sided tests. Coefficients are color-coded, and larger squares indicate stronger correlations. Significance levels are denoted by asterisks: * p ≤ 0.05, ** p ≤ 0.01, *** p ≤ 0.001. All corresponding statistical values are provided in Supplementary Data 7 and 9. b Genomic collinearity of eight contiguous fragments containing defense islands. Defense genes are highlighted in green, candidate defense genes in yellow, and associated genes are color-coded: transport-related genes (orange), mobile genetic elements (MGEs; pink), other annotated functional genes (purple), and unknown functions (gray).

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