Fig. 4: Schematic maps of virulence plasmids. | Nature Communications

Fig. 4: Schematic maps of virulence plasmids.

From: Genomic dissection of the clonal background and global dissemination of hypervirulent Klebsiella pneumoniae CG23-KL57 lineage

Fig. 4: Schematic maps of virulence plasmids.

A Alignment of the ST218-KL57 virulence plasmids with pSGH10. B Alignment of the ST23-KL57 virulence plasmids with pSGH10. The innermost circle shows the GC skew (GC-skew, calculated as (G − C)/(G + C)) with a window size of 500 bp and a step size of 20 bp. Inward indicates that the G content is relatively higher than the C content (G > C), while outward indicates that the G content is relatively lower than the C content (G < C); The next inner circle shows the G and C content. Inward indicates that the G and C content is below the average, while outward indicates that it is above the average; The outermost circle shows the arrangement of genes, where forward genes are displayed in the clockwise direction and reverse genes in the counterclockwise direction. C–E Organization of the deletion regions in the virulence plasmids of ST218-KL57 and ST23-KL57, compared to the corresponding reference regions. Genes are represented by arrows, and shaded regions indicate areas of homology (> 95% nucleotide identity). The accession numbers for pSGH10, pKp_Goe_414-2, and pZ360 are NZ_CP025081.1, NZ_CP018338.1, and NZ_JBQABA010000002.1, respectively. Source data are provided as a Source Data file.

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