Fig. 3: Association of mdr1 deletion with antimalarial susceptibility. | Nature Communications

Fig. 3: Association of mdr1 deletion with antimalarial susceptibility.

From: A common DNA deletion altering the 3’UTR of mdr1 is associated with reduced mefloquine susceptibility in P. vivax parasites from Cambodian patients

Fig. 3: Association of mdr1 deletion with antimalarial susceptibility.

A Distributions of slope half-life following in vivo artesunate treatment of patients infected with parasites with deletion (n = 138 infections) and without deletion (n = 29 infections). We performed two-sided unpaired t-tests without adjustments for multiple comparisons (p = 0.2311). Source data are provided as a Source Data file. B Distributions of IC50 of parasites with deletion (n = 9 infections) and without deletion (n = 5 infections) when exposed to mefloquine ex vivo. We performed two-sided unpaired t-tests without adjustments for multiple comparisons (p = 0.0496). Source data are provided as a Source Data file.

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