Table 1 Key pluripotency-associated and NCC-specifier genes are differentially expressed in Nr6a1 null embryos compared to control littermates
From: NR6A1 is essential for neural crest cell specification, formation and survival
scRNA-seq | |||
|---|---|---|---|
Gene | log2(Nr6a1 Null/WT) | Adjusted P value | Cell Population |
Oct4 | 4.107 | 5.86E-04 | NPB |
Nanog | 5.379 | 3.03E-05 | NPB |
Sox10 | −1.961 | 7.85E-06 | NCC |
RNA-seq | |||
Oct4 | 5.854 | 2.54E-117 | bulk |
Nanog | 4.378 | 4.70E-34 | bulk |
Snai1 | −0.955 | 1.71E-06 | bulk |
Foxd3 | −0.855 | 0.031 | bulk |
Sox9 | −0.293 | 0.147 | bulk |
Sox10 | −1.293 | 1.89E-11 | bulk |
Zeb2 | 0.159 | 0.484 | bulk |
Twist1 | −0.612 | 0.001 | bulk |
Microarray | |||
Oct4 | 5.379 | 0.014 | bulk |
Nanog | 3.408 | 0.014 | bulk |
Snai1 | −0.256 | 0.373 | bulk |
Foxd3 | −0.355 | 0.235 | bulk |
Sox9 | −0.380 | 0.120 | bulk |
Sox10 | −0.125 | 0.574 | bulk |
Zeb2 | −0.325 | 0.205 | bulk |
Twist1 | −0.121 | 0.656 | bulk |
